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  • Protease-Activated Receptor-4 Antibodies

Invitrogen

Protease-Activated Receptor-4 Polyclonal Antibody

View all (9) Protease-Activated Receptor-4 antibodies

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Datasheet
Protocols
Questions & Answers

Cite Protease-Activated Receptor-4 Polyclonal Antibody

  • Antibody Testing Data (1)
Protease-Activated Receptor-4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Protease-Activated Receptor-4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Protease-Activated Receptor-4 Antibody (PA5-33531) in IHC (P)

Immunohistochemistry analysis of Protease-Activated Receptor-4 in human lung, respiratory epithelium. Samples were incubated with Protease-Activated Receptor-4 polyclonal antibody (Product # PA5-33531). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Protease-Activated Receptor-4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Protease-Activated Receptor-4 Polyclonal Antibody

Product Details

PA5-33531

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

6-13 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 16 amino acid peptide from N-terminal extracellular domain of human F2RL3 / PAR4.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2550911

Product Specific Information

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey, Marmoset (94%) Mouse, Pig (88%) Bovine, Elephant (81%).

Target Information

Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: coagulation factor II (thrombin) receptor-like 3; Coagulation factor II receptor-like 3; PAR-4; protease-activated receptor-4; Proteinase-activated receptor 4; Thrombin receptor-like 3

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Gene Aliases: F2RL3; PAR4

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UniProt ID: (Human) Q96RI0

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Entrez Gene ID: (Human) 9002

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Function(s)
G-protein coupled receptor activity thrombin receptor activity
Process(es)
signal transduction phospholipase C-activating G-protein coupled receptor signaling pathway blood coagulation response to wounding platelet activation positive regulation of release of sequestered calcium ion into cytosol platelet dense granule organization thrombin receptor signaling pathway
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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