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Invitrogen
Phospho-MARCKS (Ser170) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-MARCKS (Ser170) Antibody (PA5-37633) in IHC (P)
Product Details
PA5-37633
Species Reactivity
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Conjugate
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Product Specific Information
A suggested positive control for Western blot is MCF-7 cells; suggested positive control for IHC is human lung carcinoma.
Target Information
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: 80K-L protein; FLJ14368; FLJ90045; MARCKS; MARCS; Myristoylated alanine-rich C-kinase substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; Protein kinase C substrate, 80 kDa protein, light chain
Gene Aliases: 80K-L; MACS; MARCKS; PKCSL; PRKCSL
UniProt ID: (Human) P29966
Entrez Gene ID: (Human) 4082
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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