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  • Lamin A/C Antibodies

Invitrogen

Phospho-Lamin A/C (Ser22) Recombinant Rabbit Monoclonal Antibody (LaminACS22-CF12), APC

View all (48) Lamin A/C antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Phospho-Lamin A/C (Ser22) Recombinant Rabbit Monoclonal Antibody (LaminACS22-CF12), APC

  • Antibody Testing Data (1)
Phospho-Lamin A/C (Ser22) Antibody in Flow Cytometry (Flow)
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Phospho-Lamin A/C (Ser22) Antibody in Flow Cytometry (Flow)
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Phospho-Lamin A/C (Ser22) Antibody (MA5-37184) in Flow

Flow cytometry of Phospho-Lamin A/C (Ser22) using HeLa cells. Samples were incubated in monoclonal Phospho-Lamin A/C (Ser22) antibody (Product # MA5-37184). Images correspond with the following conditions: untreated (black), treated with nocodazole (blue). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Phospho-Lamin A/C (Ser22) Antibody in Flow Cytometry (Flow)
Phospho-Lamin A/C (Ser22) Recombinant Rabbit Monoclonal Antibody (LaminACS22-CF12), APC

Product Details

MA5-37184

Applications
Tested Dilution
Publications

Flow Cytometry (Flow)

5 µL/1x10^6 cells
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

LaminACS22-CF12

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Ser22 of human phospho Lamin A/C.
View immunogen

Conjugate

APC APC APC
  • Unconjugated
  • FITC
  • PE 
  • Request custom conjugation

Excitation/Emission Max

651/660 nm View spectra spectra

Form

Liquid

Purification

Protein A/G

Storage buffer

PBS with 0.20% BSA

Contains

0.09% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2897118

Target Information

Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

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Bioinformatics

Protein Aliases: 70 kDa lamin; Lamin A+C mutant; lamin a-c; lamin A/C-like 1; Lamin AC; lamin C; lamin-A/C; mutant 453W; Mutant lamin A/C; Prelamin-A/C; progerin mutant; renal carcinoma antigen NY-REN-32; RP11-54H19.1

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Gene Aliases: CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; LMNL1; PRO1

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UniProt ID: (Human) P02545, (Mouse) P48678

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Entrez Gene ID: (Human) 4000, (Mouse) 16905

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Function(s)
structural molecule activity protein binding protein phosphatase 1 binding
Process(es)
nucleus organization nuclear envelope organization muscle organ development establishment of cell polarity regulation of cell migration establishment or maintenance of microtubule cytoskeleton polarity protein localization to nucleus sterol regulatory element binding protein import into nucleus ventricular cardiac muscle cell development negative regulation of release of cytochrome c from mitochondria positive regulation of cell aging regulation of protein localization to nucleus negative regulation of extrinsic apoptotic signaling pathway mitotic nuclear envelope disassembly mitotic nuclear envelope reassembly spermatogenesis response to mechanical stimulus IRE1-mediated unfolded protein response positive regulation of osteoblast differentiation cellular response to hypoxia negative regulation of adipose tissue development
It has to be done as per old AB suggested Products section.
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