Invitrogen

Phospho-EphA2 (Ser897) Polyclonal Antibody

View all (44) EphA2 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers
Phospho-EphA2 (Ser897) Polyclonal Antibody

Product Details

PA5-117243

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic phosphorylated peptide around S897 of human EPHA2 (NP_0044222)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.51 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2901873

Product Specific Information

Positive Samples: NIH/3T3

Immunogen sequence: LPSTS

Target Information

EPHA2 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA2 is overexpressed in many types of human cancers. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: ephrin receptor EphA2; Ephrin type-A receptor 2; Epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; soluble EPHA2 variant 1; Tyrosine-protein kinase receptor ECK; Tyrosine-protein kinase receptor MPK-5; Tyrosine-protein kinase receptor SEK-2

View more View less

Gene Aliases: ARCC2; AW545284; CTPA; CTPP1; CTRCT6; ECK; EPHA2; Myk2; Sek-2; Sek2

View more View less

UniProt ID: (Human) P29317, (Mouse) Q03145

View more View less

Entrez Gene ID: (Human) 1969, (Mouse) 13836, (Rat) 366492

View more View less

Function(s)
transmembrane receptor protein tyrosine kinase activity ephrin receptor activity protein binding ATP binding cadherin binding involved in cell-cell adhesion nucleotide binding protein kinase activity protein tyrosine kinase activity kinase activity transferase activity transferase activity, transferring phosphorus-containing groups
Process(es)
skeletal system development angiogenesis blood vessel development vasculogenesis osteoblast differentiation protein phosphorylation apoptotic process cell adhesion transmembrane receptor protein tyrosine kinase signaling pathway intrinsic apoptotic signaling pathway in response to DNA damage regulation of lamellipodium assembly notochord formation phosphorylation cell migration peptidyl-tyrosine phosphorylation neural tube development cell differentiation neuron differentiation keratinocyte differentiation osteoclast differentiation mammary gland epithelial cell proliferation regulation of cell adhesion mediated by integrin post-anal tail morphogenesis protein kinase B signaling regulation of blood vessel endothelial cell migration regulation of angiogenesis bone remodeling ephrin receptor signaling pathway axial mesoderm formation notochord morphogenesis negative regulation of protein kinase B signaling notochord cell development cell chemotaxis branching involved in mammary gland duct morphogenesis lens fiber cell morphogenesis regulation of ERK1 and ERK2 cascade response to growth factor positive regulation of establishment of protein localization to plasma membrane activation of GTPase activity multicellular organism development viral process cell-cell adhesion
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support