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Invitrogen
Phospho-EIF4B (Ser497) Polyclonal Antibody
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FIGURE: 1 / 4
Phospho-EIF4B (Ser497) Antibody (PA5-105537) in IHC (P)
Product Details
PA5-105537
Species Reactivity
Host/Isotype
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Type
Immunogen
Conjugate
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RRID
Product Specific Information
Antibody detects endogenous levels of eIF4B only when phosphorylated at Ser497.
Target Information
The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: eIF-4B; Eukaryotic translation initiation factor 4B; hCG_2014609
Gene Aliases: 2310046H11Rik; AL024095; C85189; EIF-4B; Eif4a2; EIF4B; PRO1843
UniProt ID: (Human) P23588, (Mouse) Q8BGD9
Entrez Gene ID: (Human) 1975, (Rat) 300253, (Mouse) 75705
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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