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Phospho-EIF4B (Ser406) Recombinant Rabbit Monoclonal Antibody (5G14)

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Phospho-EIF4B (Ser406) Recombinant Rabbit Monoclonal Antibody (5G14)

  • Antibody Testing Data (1)
Phospho-EIF4B (Ser406) Antibody in Western Blot (WB)
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Phospho-EIF4B (Ser406) Antibody in Western Blot (WB)
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Phospho-EIF4B (Ser406) Antibody (80059-1-RR100UL) in WB

Non-treated and Calyculin A treated cells were subjected to SDS PAGE followed by western blot with (Product # 80059-1-RR100UL) (Phospho-EIF4B (Ser406) antibody) at dilution of 1:2,000 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Phospho-EIF4B (Ser406) Antibody in Western Blot (WB)
Phospho-EIF4B (Ser406) Recombinant Rabbit Monoclonal Antibody (5G14)

Product Details

80059-1-RR100UL

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:4,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

proprietary

Class

Recombinant Monoclonal

Type

Antibody

Clone

5G14

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Target Information

The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: eIF-4B; Eukaryotic translation initiation factor 4B; hCG_2014609

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Gene Aliases: 2310046H11Rik; AL024095; C85189; EIF-4B; Eif4a2; EIF4B; PRO1843

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UniProt ID: (Human) P23588, (Mouse) Q8BGD9

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Entrez Gene ID: (Human) 1975, (Rat) 300253, (Mouse) 75705

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Function(s)
nucleotide binding RNA binding translation initiation factor activity helicase activity protein binding RNA strand annealing activity RNA strand-exchange activity ribosomal small subunit binding poly(A) RNA binding nucleic acid binding
Process(es)
translational initiation nuclear-transcribed mRNA poly(A) tail shortening formation of translation preinitiation complex cytoplasmic translation regulation of translational initiation eukaryotic translation initiation factor 4F complex assembly translation
It has to be done as per old AB suggested Products section.
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