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  • Cytokeratin 8 Antibodies

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Phospho-Cytokeratin 8 (Ser431) Polyclonal Antibody

View all (103) Cytokeratin 8 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Phospho-Cytokeratin 8 (Ser431) Polyclonal Antibody

  • Antibody Testing Data (1)
Phospho-Cytokeratin 8 (Ser431) Antibody in Western Blot (WB)
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Phospho-Cytokeratin 8 (Ser431) Antibody in Western Blot (WB)
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Phospho-Cytokeratin 8 (Ser431) Antibody (BS-12920R) in WB

Mouse stomach lysates probed with Cytokeratin 8 (Ser431) Polyclonal Antibody, Unconjugated (bs-12920R) at 1:300 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37°C. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Phospho-Cytokeratin 8 (Ser431) Antibody in Western Blot (WB)
Phospho-Cytokeratin 8 (Ser431) Polyclonal Antibody

Product Details

BS-12920R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic phosphopeptide derived from human CK8 around the phosphorylation site of Ser431.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CK-8; cytokeratin 8; Cytokeratin endo A; Cytokeratin-8; K8; keratin 8, type II; keratin complex 2, basic, gene 8; Keratin, type II cytoskeletal 8; Keratin-8; Type-II keratin Kb8

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Gene Aliases: AA960620; AL022697; AU019895; CARD2; CK-8; CK8; CYK8; EndoA; K2C8; K8; KO; Krt-2.8; Krt2-8; KRT8

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UniProt ID: (Human) P05787, (Mouse) P11679

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Entrez Gene ID: (Human) 3856, (Mouse) 16691

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Function(s)
structural molecule activity protein binding protein complex binding scaffold protein binding
Process(es)
cell morphogenesis involved in differentiation multicellular organism development tumor necrosis factor-mediated signaling pathway sarcomere organization response to hydrostatic pressure response to other organism cell differentiation involved in embryonic placenta development extrinsic apoptotic signaling pathway hepatocyte apoptotic process viral process
It has to be done as per old AB suggested Products section.
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