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  • PSAP Antibodies

Invitrogen

PSAP Monoclonal Antibody (3B4A8)

View all (29) PSAP antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite PSAP Monoclonal Antibody (3B4A8)

  • Antibody Testing Data (7)
PSAP Antibody in Immunocytochemistry (ICC/IF)
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PSAP Antibody in Immunocytochemistry (ICC/IF)
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PSAP Antibody (MA5-38610) in ICC/IF

Immunocytochemistry/Immunofluorescence analysis of PSAP in HeLa cells using PSAP Monoclonal Antibody (Product # MA5-38610) (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Product # 35503) {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PSAP Antibody in Immunocytochemistry (ICC/IF)
PSAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PSAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PSAP Antibody in Western Blot (WB)
PSAP Antibody in Western Blot (WB)
PSAP Antibody in Western Blot (WB)
PSAP Antibody in Flow Cytometry (Flow)
PSAP Monoclonal Antibody (3B4A8)

Product Details

MA5-38610

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:1,000
-

Immunocytochemistry (ICC/IF)

1:200-1:1,000
-

Flow Cytometry (Flow)

1:200-1:400
-
Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

3B4A8

Immunogen

Purified recombinant fragment of human PSAP (aa: 17-216) expressed in E. Coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2898522

Product Specific Information

This antibody has been tested in indirect ELISA.

Target Information

PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Proactivator polypeptide; Prosaposin; prosaposin (sulfated glycoprotein, sphingolipid hydrolase activator); SGP-1; sphingolipid activator protein-1; Sulfated glycoprotein 1

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Gene Aliases: GLBA; PSAP; SAP1; SGP-1; Sgp1; SGP1A

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UniProt ID: (Human) P07602, (Rat) P10960

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Entrez Gene ID: (Human) 5660, (Rat) 25524

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Function(s)
G-protein coupled receptor binding protein binding enzyme activator activity lipid binding
Process(es)
platelet degranulation glycosphingolipid metabolic process lipid transport adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway regulation of autophagy regulation of lipid metabolic process positive regulation of catalytic activity positive regulation of MAPK cascade prostate gland growth epithelial cell differentiation involved in prostate gland development cellular response to organic substance negative regulation of hydrogen peroxide-induced cell death sphingolipid metabolic process regulation of MAPK cascade glycolipid transport developmental growth
It has to be done as per old AB suggested Products section.
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