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  • PSAP Antibodies

Proteintech

PSAP Polyclonal Antibody

View all (29) PSAP antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite PSAP Polyclonal Antibody

  • Antibody Testing Data (6)
PSAP Antibody in Immunocytochemistry (ICC/IF)
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PSAP Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 6

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PSAP Antibody (18396-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed HepG2 cells using 18396-1-AP (PSAP antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PSAP Antibody in Immunocytochemistry (ICC/IF)
PSAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PSAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PSAP Antibody in Western Blot (WB)
PSAP Antibody in Western Blot (WB)
PSAP Antibody in Western Blot (WB)
PSAP Polyclonal Antibody

Product Details

18396-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Immunocytochemistry (ICC/IF)

1:50-1:500
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PSAP Fusion Protein Ag13263 (61-143 aa encoded by BC001503)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.39 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody should recognize saposin A.

Immunogen sequence: LPCDICKDV VTAAGDMLKD NATEEEILVY LEKTCDWLPK PNMSASCKEI VDSYLPVILD IIKGEMSRPG EVCSALNLCE SLQK (61-143 aa encoded by BC001503)

Target Information

PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Proactivator polypeptide; Prosaposin; SGP-1; snoRNA MBII-198; sphingolipid activator protein-1; Sulfated glycoprotein 1

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Gene Aliases: AI037048; GLBA; PSAP; SAP1; SGP-1; Sgp1

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UniProt ID: (Human) P07602, (Mouse) Q61207

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Entrez Gene ID: (Human) 5660, (Mouse) 19156

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Function(s)
G-protein coupled receptor binding protein binding enzyme activator activity lipid binding
Process(es)
platelet degranulation glycosphingolipid metabolic process lipid transport adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway regulation of autophagy regulation of lipid metabolic process positive regulation of catalytic activity positive regulation of MAPK cascade prostate gland growth epithelial cell differentiation involved in prostate gland development cellular response to organic substance negative regulation of hydrogen peroxide-induced cell death lipid metabolic process sphingolipid metabolic process regulation of MAPK cascade developmental growth
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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