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Invitrogen
PRP8 Recombinant Rabbit Monoclonal Antibody (4I1Q8)
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Product Details
MA5-38118
Species Reactivity
Host/Isotype
Expression System
Class
Type
Clone
Immunogen
Conjugate
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Product Specific Information
Positive Samples: HeLa, 293T, Jurkat, Mouse brain, Mouse spleen
Immunogen sequence: MADNPSWDGE KTIIITCSFT PGSCTLTAYK LTPSGYEWGR QNTDKGNNPK GYLPSHYERV QMLLSDRFLG FFMVPAQSSW NYNFMGVRHD PNMKYELQLA NPKEFYHEVH RPSHFLNFAL LQEGEVYSAD REDLYA
Target Information
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: 220 kDa U5 snRNP-specific protein; apoptosis-regulated protein 1; apoptosis-regulated protein 2; H PRPC8; p220; Pre-mRNA-processing-splicing factor 8; precursor mRNA processing protein; PRP8 homolog; PRP8 pre-mRNA processing factor 8 homolog; spl; Splicing factor Prp8; U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p
Gene Aliases: AU019467; D11Bwg0410e; DBF3/PRP8; HPRP8; PRP8; PRPC8; PRPF8; RP13; Sfprp8l; SNRNP220
UniProt ID: (Human) Q6P2Q9, (Mouse) Q99PV0
Entrez Gene ID: (Human) 10594, (Rat) 287530, (Mouse) 192159
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