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Proteintech
PRLR Monoclonal Antibody (2E10G5)
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Product Details
67292-1-IG
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
Prolactin (PRL) is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. PRL exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane PRL receptor. Immunoreactive PRL receptor (PRLR), a member of the cytokine receptor family, varies in size (short and long forms) with tissue source and species, from ~40 kDa to 100 kDa. PRLR consists of at least three separate domains: an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region, the length of which appears to influence ligand binding and regulate cellular function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hPRL receptor; Prl R; PRL-R; Prolactin receptor; prolactin receptor related sequence 1; secreted prolactin binding protein
Gene Aliases: AI987712; HPRL; hPRLrI; MFAB; Pr-1; Pr-3; PRLR; Prlr-rs1
UniProt ID: (Human) P16471, (Mouse) P15213
Entrez Gene ID: (Human) 5618, (Mouse) 19116
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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