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  • PPT1 Antibodies

Invitrogen

PPT1 Monoclonal Antibody (OTI1F10)

View all (22) PPT1 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite PPT1 Monoclonal Antibody (OTI1F10)

  • Antibody Testing Data (7)
PPT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PPT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 7

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PPT1 Antibody (MA5-26471) in IHC (P)

Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human breast tissue. To expose target proteins, 10mM citric buffer, pH6.0, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a PPT1 monoclonal antibody (Product # MA5-26471). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PPT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPT1 Antibody in Western Blot (WB)
PPT1 Antibody in Western Blot (WB)
PPT1 Monoclonal Antibody (OTI1F10)

Product Details

MA5-26471

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:500
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI1F10

Immunogen

Human recombinant protein fragment corresponding to amino acids 100-306 of PPT1 produced in E.coli
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2725101

Target Information

The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 3.1.2.22; ceroid-palmitoyl-palmitoyl-protein thioesterase 1; Palmitoyl-protein hydrolase 1; Palmitoyl-protein thioesterase 1; PPT-1

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Gene Aliases: CLN1; INCL; PPT; PPT1

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UniProt ID: (Human) P50897

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Entrez Gene ID: (Human) 5538

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Function(s)
palmitoyl-(protein) hydrolase activity palmitoyl-CoA hydrolase activity
Process(es)
protein depalmitoylation receptor-mediated endocytosis pinocytosis lysosomal lumen acidification chemical synaptic transmission neurotransmitter secretion nervous system development brain development visual perception grooming behavior associative learning adult locomotory behavior protein transport lipid catabolic process sphingolipid catabolic process protein catabolic process negative regulation of cell growth membrane raft organization regulation of phospholipase A2 activity long-chain fatty-acyl-CoA biosynthetic process negative regulation of apoptotic process negative regulation of neuron apoptotic process cellular protein catabolic process positive regulation of receptor-mediated endocytosis positive regulation of pinocytosis neuron development regulation of synapse structure or activity response to stimulus cofactor transport cofactor metabolic process
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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