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Proteintech
PPP2R1B Polyclonal Antibody
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Product Details
12621-1-AP
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Shipping conditions
Product Specific Information
Immunogen sequence: ELGENLPIE DRETIIMNQI LPYIKELVSD TNQHVKSALA SVIMGLSTIL GKENTIEHLL PLFLAQLKDE CPDVRLNIIS NLDCVNEVIG IRQLSQSLLP AIVELAEDAK WRVRLAIIEY MPLLAGQLGV EFFDEKLNSL CMAWLVDHVY AIREAATNNL MKLVQKFGTE WAQNTIVPKV LVMANDPNYL HRMTTLFCIN ALSEACGQEI TTKQMLPIVL KMAGDQVANV RFNVAKSLQK IGPILDTNAL QGEVKPVLQK LGQDEDMDVK YFAQEAISVV AQRLRKLEFP VKDSGEPSVP RADKNHFPRP TVPGEDMGKG PVYQLRGDTR DTLAQLGIAE LVHFSQSTD (320-667 aa encoded by BC027596)
Target Information
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2A alpha and PP2A beta. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A alpha and -A beta, PP2A-B alpha and -B beta, PP2A-C alpha and -C beta, and PP2A-B56 alpha and -B56 beta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: PP2A -AR1 beta; PP2A A beta; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta; PP2A, subunit A, PR65-beta isoform; PP2A, subunit A, R1-beta isoform; PP2A-A beta; PP2A-APR65 beta; PP2AA beta; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform; protein phosphatase 2 regulatory subunit A, beta; protein phosphatase 2, regulatory subunit A, beta; protein phosphatase 2, structural/regulatory subunit A, beta; Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
Gene Aliases: 2410091N08Rik; AI790395; PP2A-Abeta; PPP2R1B; PR65B
UniProt ID: (Human) P30154, (Mouse) Q7TNP2, (Rat) Q4QQT4
Entrez Gene ID: (Human) 5519, (Mouse) 73699, (Rat) 315648
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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