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Invitrogen
PPP1R8 Polyclonal Antibody
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Product Details
PA5-55605
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
Immunogen sequence: THSEAGSQPH GIHGTALIGG LPMPYPNLAP DVDLTPVVPS AVNMNPAPNP AVYNPEAVNE PKKKKYAKEA WPGKKPTPSL LI
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
Target Information
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: activator of RNA decay; NIPP-1; Nuclear inhibitor of protein phosphatase 1; nuclear inhibitor of protein phosphatase-1 alpha; nuclear inhibitor of protein phosphatase-1 beta; nuclear subunit of PP-1; Protein phosphatase 1 regulatory inhibitor subunit 8; protein phosphatase 1, regulatory (inhibitor) subunit 8; protein phosphatase 1, regulatory subunit 8; RNase E
Gene Aliases: 6330548N22Rik; ARD-1; ARD1; AU044684; NIPP-1; NIPP1; PPP1R8; PRO2047
UniProt ID: (Human) Q12972, (Mouse) Q8R3G1
Entrez Gene ID: (Human) 5511, (Rat) 313030, (Mouse) 100336
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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