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  • PPM1B Antibodies

Proteintech

PPM1B Monoclonal Antibody (2C7H2)

View all (31) PPM1B antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite PPM1B Monoclonal Antibody (2C7H2)

  • Antibody Testing Data (3)
PPM1B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PPM1B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 3

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PPM1B Antibody (67647-1-IG) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 67647-1-Ig (PPM1B antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PPM1B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPM1B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPM1B Antibody in Western Blot (WB)

Product Details

67647-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:10,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

2C7H2

Immunogen

PPM1B Fusion Protein Ag3871

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1000 µg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Aliquoting is unnecessary for -20°C storage.

Target Information

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: PP2C-beta; Protein phosphatase 1B; protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform; Protein phosphatase 2C isoform beta; protein phosphatase 2C-like protein; protein phosphatase, Mg2+/Mn2+ dependent, 1B; Ser/Thr protein phosphatase type 2C beta 2 isoform

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Gene Aliases: PP2C-beta; PP2C-beta-X; PP2CB; PP2CBETA; PPC2BETAX; PPM1B

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UniProt ID: (Human) O75688

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Entrez Gene ID: (Human) 5495

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Function(s)
magnesium ion binding protein serine/threonine phosphatase activity protein binding manganese ion binding
Process(es)
protein dephosphorylation N-terminal protein myristoylation negative regulation of interferon-beta production peptidyl-threonine dephosphorylation negative regulation of NF-kappaB import into nucleus negative regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of defense response to virus
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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