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  • Primary Antibodies ›
  • PPM1B Antibodies

Invitrogen

PPM1B Polyclonal Antibody

View all (31) PPM1B antibodies

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Datasheet
Protocols
Questions & Answers

Cite PPM1B Polyclonal Antibody

  • Antibody Testing Data (2)
PPM1B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PPM1B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 2

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PPM1B Antibody (PA5-148260) in IHC (P)

Immunohistochemistry analysis of PPM1B in formalin-fixed paraffin embedded human kidney sections. Samples were incubated with PPM1B polyclonal antibody (Product # PA5-148260) using a dilution of 1:100. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PPM1B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPM1B Antibody in Western Blot (WB)

Product Details

PA5-148260

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

E. coli-derived Human PPM1B fragment

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

100 µg/mL

Purification

Antigen affinity chromatography, Protein A

Storage buffer

PBS, pH 7

Contains

0.03% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3247429

Target Information

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: PP2C-beta; Protein phosphatase 1B; protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform; Protein phosphatase 2C isoform beta; protein phosphatase 2C-like protein; protein phosphatase, Mg2+/Mn2+ dependent, 1B; Ser/Thr protein phosphatase type 2C beta 2 isoform

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Gene Aliases: PP2C-beta; PP2C-beta-X; PP2CB; PP2CBETA; PPC2BETAX; PPM1B

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UniProt ID: (Human) O75688

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Entrez Gene ID: (Human) 5495

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Function(s)
magnesium ion binding protein serine/threonine phosphatase activity protein binding manganese ion binding
Process(es)
protein dephosphorylation N-terminal protein myristoylation negative regulation of interferon-beta production peptidyl-threonine dephosphorylation negative regulation of NF-kappaB import into nucleus negative regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of defense response to virus
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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