Disclaimer

Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

  • Primary Antibodies ›
  • PPM1A Antibodies

Invitrogen

PPM1A Polyclonal Antibody

View all (18) PPM1A antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite PPM1A Polyclonal Antibody

  • Antibody Testing Data (8)
PPM1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Group 53 Created with Sketch.
PPM1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Group 53 Created with Sketch.

FIGURE: 1 / 8

{{ $ctrl.currentElement.advancedVerification.fullName }}
{{ $ctrl.currentElement.advancedVerification.text }}

PPM1A Antibody (PA5-118181) in IHC (P)

Immunohistochemical staining of human PPM1A in human breast carcinoma with PPM1A Polyclonal Antibody (Product # PA5-118181, 1:3,000 dilution, formalin-fixed paraffin embedded sections). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
Published figure supplied by benchsci-logo
PMID: {{$ctrl.currentElement.benchSciPubmedId}}
View Product

{{$ctrl.videoDesc}}

{{$ctrl.videoLongDesc}}

PPM1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPM1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPM1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPM1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPM1A Antibody in Western Blot (WB)
PPM1A Antibody in Western Blot (WB)
PPM1A Antibody in Immunoprecipitation (IP)
PPM1A Antibody in Immunoprecipitation (IP)

Product Details

PA5-118181

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:5,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:5,000
-

ELISA (ELISA)

1:5,000-1:10,000
-

Immunoprecipitation (IP)

1-5 µL/mg of lysate
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human PPM1A Protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography, Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2902781

Target Information

PPM1A (Protein phosphatase 1A) is also named as PPPM1A and belongs to the PP2C family. It is a serine/threonine protein phosphatase that is essential for regulating cellular stress responses in eukaryotes. PPM1A plays an important role in tumor suppression and that it negatively controls many signaling pathways which are critical for trophoblast invasion. This protein distributes in both the cytoplasm and nucleus of mammalian cells. It has 2 isoforms produced by alternative splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: PP2C-alpha; Protein phosphatase 1A; protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform; Protein phosphatase 2C isoform alpha; Protein phosphatase IA; protein phosphatase, Mg2+/Mn2+ dependent, 1A

View more View less

Gene Aliases: PP2C-ALPHA; PP2CA; PP2Calpha; PPM1A; PPPM1A

View more View less

UniProt ID: (Human) P35813

View more View less

Entrez Gene ID: (Human) 5494

View more View less

Function(s)
magnesium ion binding protein serine/threonine phosphatase activity signal transducer activity protein binding manganese ion binding calmodulin-dependent protein phosphatase activity R-SMAD binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter protein dephosphorylation N-terminal protein myristoylation cell cycle arrest negative regulation of SMAD protein complex assembly Wnt signaling pathway dephosphorylation positive regulation of Wnt signaling pathway negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of BMP signaling pathway peptidyl-threonine dephosphorylation negative regulation of NF-kappaB import into nucleus positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of transcription, DNA-templated positive regulation of protein export from nucleus cellular response to transforming growth factor beta stimulus
It has to be done as per old AB suggested Products section.
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support

Your items have has been added!


Host server : magellan-search-c7d89468c-sbmwt:80/100.66.128.142:80.
git-commit: 4db89d68e0ee702f860d53b64def1eb94897fade
git-url: https://github.com/thermofisher/magellan-search
git-branch: release/2.36.2-2025.09.39-1.0