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  • PPAT Antibodies

OriGene

PPAT Monoclonal Antibody (OTI1B11), TrueMAB™

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Cite PPAT Monoclonal Antibody (OTI1B11), TrueMAB™

  • Antibody Testing Data (9)
PPAT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PPAT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 9

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PPAT Antibody (CF504706) in IHC (P)

Immunohistochemical staining of paraffin-embedded human pancreas tissue within the normal limits using anti-PPAT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, TA504706) {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PPAT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPAT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPAT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPAT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPAT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPAT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPAT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPAT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PPAT Antibody in Western Blot (WB)
PPAT Monoclonal Antibody (OTI1B11), TrueMAB™

Product Details

CF504706

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-

Immunohistochemistry (Paraffin) (IHC (P))

1:150
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI1B11

Immunogen

Human recombinant protein fragment corresponding to amino acids 42-278 of human PPAT produced in E.coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. This gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Amidophosphoribosyltransferase; ATase; EC 2.4.2.14; glutamine phosphoribosylpyrophosphatate amidotransferase; Glutamine phosphoribosylpyrophosphate amidotransferase; glutamine PRPP amidotransferase; GPAT

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Gene Aliases: ATASE; GPAT; PPAT; PRAT

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UniProt ID: (Human) Q06203

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Entrez Gene ID: (Human) 5471

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Function(s)
amidophosphoribosyltransferase activity metal ion binding 4 iron, 4 sulfur cluster binding
Process(es)
G1/S transition of mitotic cell cycle kidney development purine nucleotide biosynthetic process 'de novo' IMP biosynthetic process glutamine catabolic process lactation purine nucleobase biosynthetic process nucleoside metabolic process purine ribonucleoside monophosphate biosynthetic process organ regeneration cellular response to insulin stimulus cellular response to drug protein homotetramerization maternal process involved in female pregnancy
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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