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  • PMEPA1 Antibodies

NeoBiotechnologies

PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Recombinant Rabbit Monoclonal Antibody (PMEPA1/6421R)

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Datasheet
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Cite PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Recombinant Rabbit Monoclonal Antibody (PMEPA1/6421R)

  • Antibody Testing Data (3)
PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Antibody (56937-RBM11-P1ABX) in IHC (P)

Formalin-fixed, paraffin-embedded human prostate carcinoma stained with PMEPA1 Recombinant Rabbit Monoclonal Antibody (PMEPA1/6421R). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Antibody in SDS-PAGE (SDS-PAGE)
PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Recombinant Rabbit Monoclonal Antibody (PMEPA1/6421R)

Product Details

56937-RBM11-P1ABX

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

PMEPA1/6421R

Immunogen

Recombinant full-length human PMEPA1 protein
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Prostate transmembrane protein androgen induced 1; Protein TMEPAI; Solid tumor-associated 1 protein; Transmembrane prostate androgen-induced protein; transmembrane, prostate androgen induced RNA

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Gene Aliases: PMEPA1; STAG1; TMEPAI

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UniProt ID: (Human) Q969W9

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Entrez Gene ID: (Human) 56937

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Function(s)
protein binding WW domain binding R-SMAD binding
Process(es)
negative regulation of SMAD protein complex assembly negative regulation of transforming growth factor beta receptor signaling pathway androgen receptor signaling pathway negative regulation of pathway-restricted SMAD protein phosphorylation
It has to be done as per old AB suggested Products section.
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