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  • PMEPA1 Antibodies

NeoBiotechnologies

PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Monoclonal Antibody (PMEPA1, 2696)

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Datasheet
Protocols
Questions & Answers

Cite PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Monoclonal Antibody (PMEPA1, 2696)

  • Antibody Testing Data (5)
PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 5

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PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Antibody (56937-MSM6-P1ABX) in IHC (P)

Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human prostate carcinoma using PMEPA1, TMEPAI (Tumor Suppressor Oncoprotein) Monoclonal Antibody (Product # 56937-MSM6-P1ABX). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Antibody in Peptide array (ARRAY)
PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Antibody in SDS-PAGE (SDS-PAGE)
PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Monoclonal Antibody (PMEPA1, 2696)

Product Details

56937-MSM6-P1ABX

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL
-

Peptide Array (Array)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

PMEPA1, 2696

Immunogen

Recombinant full-length human PMEPA1 protein
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

Target Information

This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Prostate transmembrane protein androgen induced 1; Protein TMEPAI; Solid tumor-associated 1 protein; Transmembrane prostate androgen-induced protein; transmembrane, prostate androgen induced RNA

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Gene Aliases: PMEPA1; STAG1; TMEPAI

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UniProt ID: (Human) Q969W9

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Entrez Gene ID: (Human) 56937

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Function(s)
protein binding WW domain binding R-SMAD binding
Process(es)
negative regulation of SMAD protein complex assembly negative regulation of transforming growth factor beta receptor signaling pathway androgen receptor signaling pathway negative regulation of pathway-restricted SMAD protein phosphorylation
It has to be done as per old AB suggested Products section.
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