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Proteintech
PLSCR3 Polyclonal Antibody
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Product Details
28028-1-AP
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: MAGYLPPKG YAPSPPPPYP VTPGYPEPAL HPGPGQAPVP AQVPAPAPGF ALFPSPGPVA LGSAAPFLPL PGVPSGLEFL VQIDQILIHQ KAERVETFLG WETCNRYELR SGAGQPLGQA AEESNCCARL CCGARRPLRV RLADPGDREL LRLLRPLHCG CSCCPCGLQE MEVQAPPGTT IGHVLQTWHP FLPKFSIQDA DRQTVLRVVG PCWTCGCGTD TNFEVKTRDE SRSVGRISKQ WGGLVREALT DADDFGLQFP LDLDVRVKAV LLGATFLIDY MFFEKRGGAG PSAITS (1-295 aa encoded by B C011735)
Target Information
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ca 2+ dependent phospholipid scramblase 3; Ca(2+)-dependent phospholipid scramblase 3; Phospholipid scramblase 3; PL scramblase 3
Gene Aliases: 2210403O21Rik; 2610037N06Rik; ESTM3; PLSCR3; X83310
UniProt ID: (Human) Q9NRY6, (Mouse) Q9JIZ9
Entrez Gene ID: (Human) 57048, (Mouse) 70310
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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