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Proteintech
PHGDH Recombinant Rabbit Monoclonal Antibody (5L16)
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Product Details
81986-1-RR
Species Reactivity
Host/Isotype
Expression System
Class
Type
Clone
Immunogen
Conjugate
Form
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: SFGVQQLPLE EIWPLCDFIT VHTPLLPSTT GLLNDNTFAQ CKKGVRVVNC ARGGIVDEGA LLRALQSGQC AGAALDVFTE EPPRDRALVD HENVISCPHL GASTKEAQSR CGEEIAVQFV DMVKGKSLTG VVNAQALTSA FSPHTKPWIG LAEALGTLMR AWAGSPKGTI QVITQGTSLK NAGNCLSPAV IVGLLKEASK QADVNLVNAK LLVKEAGLNV TTSHSPAAPG EQGFGECLLA VALAGAPYQA VGLVQGTTPV LQGLNGAVFR PEVPLRRDLP LLLFRTQTSD PAMLPTMIGL LAEAGVRLLS YQTSLVSDGE TWHVMGISSL LPSLEAWKQH VTEAFQFHF
Target Information
PHGDH gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: 2-oxoglutarate reductase; 3-PGDH; 3-phosphoglycerate dehydrogenase; 3-phosphoglycerate dehyrogenase; A10; D-3-phosphoglycerate dehydrogenase; epididymis secretory protein Li 113; Malate dehydrogenase
Gene Aliases: 3-PGDH; 3PGDH; 4930479N23; A10; HEL-S-113; NLS; NLS1; PDG; PGAD; PGD; PGDH; PGDH3; PHGDH; PHGDHD; SERA
UniProt ID: (Human) O43175, (Mouse) Q61753, (Rat) O08651
Entrez Gene ID: (Human) 26227, (Mouse) 236539, (Rat) 58835
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