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OriGene

PDIA3 Monoclonal Antibody (OTI3E1), TrueMAB™

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Cite PDIA3 Monoclonal Antibody (OTI3E1), TrueMAB™

  • Antibody Testing Data (11)
PDIA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PDIA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PDIA3 Antibody (CF504995) in IHC (P)

Immunohistochemical staining of paraffin-embedded human pancreas tissue within the normal limits using anti-PDIA3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, TA504995) {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PDIA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PDIA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PDIA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PDIA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PDIA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PDIA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PDIA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PDIA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PDIA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PDIA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PDIA3 Antibody in Western Blot (WB)

Product Details

CF504995

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:150
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

OTI3E1

Immunogen

Human recombinant protein fragment corresponding to amino acids PDIA3 produced in E.coli.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 58 kDa glucose-regulated protein; 58 kDa microsomal protein; Disulfide isomerase ER-60; endoplasmic reticulum P58; Endoplasmic reticulum resident protein 57; Endoplasmic reticulum resident protein 60; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER p57; ER protein 57; ER protein 60; ERp 57; glucose regulated protein, 58kDa; GRP 57; GRP 58; p58; PDIA 3; phospholipase C-alpha; PI PLC; protein disulfide isomerase family A, member 3; protein disulfide isomerase-associated 3; Protein disulfide-isomerase A3

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Gene Aliases: ER60; ERP57; ERP60; ERp61; GRP57; GRP58; HEL-S-269; HEL-S-93n; HsT17083; P58; PDIA3; PI-PLC

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UniProt ID: (Human) P30101

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Entrez Gene ID: (Human) 2923

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Function(s)
protein disulfide isomerase activity cysteine-type endopeptidase activity phospholipase C activity protein binding disulfide oxidoreductase activity poly(A) RNA binding
Process(es)
antigen processing and presentation of peptide antigen via MHC class I protein folding proteolysis protein import into nucleus protein retention in ER lumen signal transduction protein folding in endoplasmic reticulum response to endoplasmic reticulum stress cell redox homeostasis oxidation-reduction process positive regulation of extrinsic apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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