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Proteintech

PDIA3 Monoclonal Antibody (3G4G7)

View all (41) ERp57 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite PDIA3 Monoclonal Antibody (3G4G7)

  • Antibody Testing Data (8)
PDIA3 Antibody in Immunocytochemistry (ICC/IF)
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PDIA3 Antibody in Immunocytochemistry (ICC/IF)
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PDIA3 Antibody (66423-1-IG) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed HEK-293 cells using 66423-1-Ig (PDIA3 antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Mouse IgG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PDIA3 Antibody in Immunocytochemistry (ICC/IF)
PDIA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PDIA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PDIA3 Antibody in Western Blot (WB)
PDIA3 Antibody in Western Blot (WB)
PDIA3 Antibody in Western Blot (WB)
PDIA3 Antibody in Western Blot (WB)
PDIA3 Antibody in Western Blot (WB)
PDIA3 Monoclonal Antibody (3G4G7)

Product Details

66423-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000-1:20,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:16,000
-

Immunocytochemistry (ICC/IF)

1:800
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

3G4G7

Immunogen

PDIA3 Fusion Protein Ag8741 (161-505 aa encoded by BC014433)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated
  • CoraLite 594
  • CoraLite Plus 488
  • Request custom conjugation

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: DDSFSEAHS EFLKAASNLR DNYRFAHTNV ESLVNEYDDN GEGIILFRPS HLTNKFEDKT VAYTEQKMTS GKIKKFIQEN IFGICPHMTE DNKDLIQGKD LLIAYYDVDY EKNAKGSNYW RNRVMMVAKK FLDAGHKLNF AVASRKTFSH ELSDFGLEST AGEIPVVAIR TAKGEKFVMQ EEFSRDGKAL ERFLQDYFDG NLKRYLKSEP IPESNDGPVK VVVAENFDEI VNNENKDVLI EFYAPWCGHC KNLEPKYKEL GEKLSKDPNI VIAKMDATAN DVPSPYEVRG FPTIYFSPAN KKLNPKKYEG GRELSDFISY LQREATNPPV IQEEKPKKKK KAQEDL (161-505 aa encoded by BC014433)

Target Information

This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 58 kDa glucose-regulated protein; 58 kDa microsomal protein; Disulfide isomerase ER-60; endoplasmic reticulum P58; endoplasmic reticulum protein; Endoplasmic reticulum resident protein 57; Endoplasmic reticulum resident protein 60; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER p57; ER protein 57; ER protein 60; ER-60 protease; ERp 57; ERp60; glucose regulated protein, 58 kDa; glucose regulated protein, 58kDa; GRP 57; GRP 58; HIP-70; oxidoreductase ERp57; p58; PDIA 3; phospholipase C, alpha; phospholipase C-alpha; PI PLC; protein disulfide isomerase associated 3; protein disulfide isomerase family A, member 3; protein disulfide isomerase-associated 3; Protein disulfide-isomerase A3; Q-2

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Gene Aliases: 58kDa; ER60; Erp; ERP57; ERP60; ERp61; GRP57; GRP58; HEL-S-269; HEL-S-93n; HsT17083; P58; PDI; PDI-Q2; PDIA3; PI-PLC; PLC[a]; Plca

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UniProt ID: (Human) P30101, (Mouse) P27773, (Rat) P11598

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Entrez Gene ID: (Human) 2923, (Mouse) 14827, (Rat) 29468

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Function(s)
protein disulfide isomerase activity cysteine-type endopeptidase activity phospholipase C activity protein binding disulfide oxidoreductase activity poly(A) RNA binding peptidase activity isomerase activity protein-disulfide reductase (glutathione) activity MHC class I protein binding
Process(es)
protein folding proteolysis response to endoplasmic reticulum stress cell redox homeostasis oxidation-reduction process cellular response to vitamin D positive regulation of protein folding positive regulation of extrinsic apoptotic signaling pathway antigen processing and presentation of peptide antigen via MHC class I protein import into nucleus protein retention in ER lumen signal transduction protein folding in endoplasmic reticulum
It has to be done as per old AB suggested Products section.
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