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Abnova

PDIA3 Polyclonal Antibody, MaxPab™

View all (41) ERp57 antibodies

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Datasheet
Protocols
Questions & Answers

Cite PDIA3 Polyclonal Antibody, MaxPab™

  • Antibody Testing Data (1)
PDIA3 Antibody in Western Blot (WB)
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PDIA3 Antibody in Western Blot (WB)
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PDIA3 Antibody (H00002923-D01P) in WB

PDIA3 MaxPab rabbit polyclonal antibody. Western Blot analysis of PDIA3 expression in HeLa. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PDIA3 Antibody in Western Blot (WB)
PDIA3 Polyclonal Antibody, MaxPab™

Product Details

H00002923-D01P

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
-

Immunocytochemistry (ICC/IF)

10-100 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PDIA3 (NP_005304.3, 1 a.a. approximately 505 a.a) full-length human protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

Product may be used with Western Blot (Cell lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MRLRRLALFP GVALLLAAAR LAAASDVLEL TDDNFESRIS DTGSAGLMLV EFFAPWCGHC KRLAPEYEAA ATRLKGIVPL AKVDCTANTN TCNKYGVSGY PTLKIFRDGE EAGAYDGPRT ADGIVSHLKK QAGPASVPLR TEEEFKKFIS DKDASIVGFF DDSFSEAHSE FLKAASNLRD NYRFAHTNVE SLVNEYDDNG EGIILFRPSH LTNKFEDKTV AYTEQKMTSG KIKKFIQENI FGICPHMTED NKDLIQGKDL LIAYYDVDYE KNAKGSNYWR NRVMMVAKKF LDAGHKLNFA VASRKTFSHE LSDFGLESTA GEIPVVAIRT AKGEKFVMQE EFSRDGKALE RFLQDYFDGN LKRYLKSEPI PESNDGPVKV VVAENFDEIV NNENKDVLIE FYAPWCGHCK NLEPKYKELG EKLSKDPNIV IAKMDATAND VPSPYEVRGF PTIYFSPANK KLNPKKYEGG RELSDFISYL QREATNPPVI QEEKPKKKKK AQEDL

Target Information

This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 58 kDa glucose-regulated protein; 58 kDa microsomal protein; Disulfide isomerase ER-60; endoplasmic reticulum P58; endoplasmic reticulum protein; Endoplasmic reticulum resident protein 57; Endoplasmic reticulum resident protein 60; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER p57; ER protein 57; ER protein 60; ERp 57; glucose regulated protein, 58 kDa; glucose regulated protein, 58kDa; GRP 57; GRP 58; p58; PDIA 3; phospholipase C, alpha; phospholipase C-alpha; PI PLC; protein disulfide isomerase family A, member 3; protein disulfide isomerase-associated 3; Protein disulfide-isomerase A3

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Gene Aliases: 58kDa; ER60; Erp; ERP57; ERP60; ERp61; GRP57; GRP58; HEL-S-269; HEL-S-93n; HsT17083; P58; PDI; PDI-Q2; PDIA3; PI-PLC; PLC[a]; Plca

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UniProt ID: (Human) P30101, (Mouse) P27773

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Entrez Gene ID: (Human) 2923, (Mouse) 14827

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Function(s)
protein disulfide isomerase activity cysteine-type endopeptidase activity phospholipase C activity protein binding disulfide oxidoreductase activity poly(A) RNA binding peptidase activity isomerase activity protein-disulfide reductase (glutathione) activity MHC class I protein binding
Process(es)
protein folding proteolysis response to endoplasmic reticulum stress cell redox homeostasis oxidation-reduction process cellular response to vitamin D positive regulation of protein folding positive regulation of extrinsic apoptotic signaling pathway antigen processing and presentation of peptide antigen via MHC class I protein import into nucleus protein retention in ER lumen signal transduction protein folding in endoplasmic reticulum
It has to be done as per old AB suggested Products section.
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