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Invitrogen
PDHA1A Polyclonal Antibody
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FIGURE: 1 / 1
PDHA1A Antibody (PA5-72684) in WB
Product Details
PA5-72684
Species Reactivity
Host/Isotype
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Type
Immunogen
Conjugate
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Target Information
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: pdha1b; PDHE1-A type I; PHE1A; pyruvate dehydrogenase (lipoamide) alpha 1; pyruvate dehydrogenase (lipoamide) alpha 1a
Gene Aliases: im:6895726; pdha1; wu:fd18b01; wu:fo96f03; zgc:73271; zgc:86692
Entrez Gene ID: (Zebrafish) 406702
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