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Bethyl Laboratories
PDCD2 Polyclonal Antibody
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FIGURE: 1 / 2
PDCD2 Antibody (A303-599A) in WB
Product Details
A303-599A
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Concentration
Purification
Storage buffer
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Shipping conditions
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Programmed cell death protein 2; Zinc finger MYND domain-containing protein 7; Zinc finger protein Rp-8
Gene Aliases: AI528543; Pcd2; PDCD2; RP-8; RP8; ZMYND7
UniProt ID: (Human) Q16342, (Mouse) P46718
Entrez Gene ID: (Human) 5134, (Mouse) 18567
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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