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Proteintech
PC Monoclonal Antibody (4F5D1)
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Product Details
66615-1-IG
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: MERVFDYSE YWEGARGLYA AFDCTATMKS GNSDVYENEI PGGQYTNLHF QAHSMGLGSK FKEVKKAYVE ANQMLGDLIK VTPSSKIVGD LAQFMVQNGL SRAEAEAQAE ELSFPRSVVE FLQGYIGVPH GGFPEPFRSK VLKDLPRVEG RPGASLPPLD LQALEKELVD RHGEEVTPED VLSAAMYPDV FAHFKDFTAT FGPLDSLNTR LFLQGPKIAE EFEVELERGK TLHIKALAVS DLNRAGQRQV FFELNGQLRS ILVKDTQAMK EMHFHPKALK DVKGQIGAPM PGKVIDIKVV AGAKVAKGQP LCVLSAMKME TVVTSPMEGT VRKVHVTKDM TLEGDDLILE IE (828-1178 aa encoded by BC011617)
Target Information
Pyruvate Carboxylase requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EC 6.4.1.1; PCB; PYC; Pyruvate carboxylase, mitochondrial; pyruvate decarboxylase; Pyruvic carboxylase
Gene Aliases: PC; PCB; Pcx
UniProt ID: (Human) P11498, (Rat) P52873
Entrez Gene ID: (Human) 5091, (Rat) 25104, (Mouse) 18563
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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