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  • PAX7 Antibodies

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PAX7 Monoclonal Antibody (1E12)

View all (34) PAX7 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite PAX7 Monoclonal Antibody (1E12)

  • Antibody Testing Data (3)
PAX7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PAX7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PAX7 Antibody (H00005081-M05) in IHC (P)

Immunoperoxidase of monoclonal antibody to PAX7 on formalin-fixed paraffin-embedded human stomach. Antibody concentration is 0.5 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PAX7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PAX7 Antibody in Western Blot (WB)
PAX7 Antibody in ELISA (ELISA)

Product Details

H00005081-M05

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

0.5 µg/mL
-

ELISA (ELISA)

3 ng/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

1E12

Immunogen

PAX7 (NP_002575.1, 411 a.a. approximately 520 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: GGLDSATSIS ASCSQRADSI KPGDSLPTSQ AYCPPTYSTT GYSVDPVAGY QYGQYGQSEC LVPWASPVPI PSPTPRASCL FMESYKVVSG WGMSISQMEK LKSSQMEQFT

Target Information

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: FLJ37460; HuP1; paired box gene 7; paired box homeotic gene 7; Paired box protein Pax-7; paired box transcription factor PAX7; paired domain gene 7; PAX7 transcriptional factor; PAX7A

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Gene Aliases: HUP1; Pax-7; PAX7; PAX7B; RMS2

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UniProt ID: (Human) P23759, (Mouse) P47239

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Entrez Gene ID: (Human) 5081, (Mouse) 18509

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Function(s)
transcription factor activity, RNA polymerase II core promoter sequence-specific transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding DNA binding protein binding
Process(es)
chromatin remodeling transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter multicellular organism development muscle organ development skeletal muscle tissue development organ morphogenesis regulation of cell fate commitment regulation of gene expression skeletal muscle satellite cell commitment spinal cord association neuron differentiation dorsal/ventral neural tube patterning positive regulation of histone methylation regulation of protein binding skeletal muscle tissue regeneration positive regulation of transcription from RNA polymerase II promoter neuron fate commitment embryonic skeletal system development cartilage development muscle tissue morphogenesis positive regulation of myoblast proliferation anatomical structure morphogenesis negative regulation of apoptotic process
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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