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  • PARL Antibodies

Proteintech

PARL Polyclonal Antibody

5 References
View all (9) PARL antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite PARL Polyclonal Antibody

  • Antibody Testing Data (9)
PARL Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PARL Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 9

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PARL Antibody (26679-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using 26679-1-AP ( PARL Antibody) at dilution of 1:200 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PARL Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PARL Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PARL Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PARL Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PARL Antibody in Western Blot (WB)
PARL Antibody in Western Blot (WB)
PARL Antibody in Western Blot (WB)
PARL Antibody in Western Blot (WB)
PARL Antibody in Western Blot (WB)
PARL Polyclonal Antibody

Product Details

26679-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
View 3 publications 3 publications

Immunohistochemistry (IHC)

-
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500
-

Not applicable (N/A)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PARL Fusion Protein Ag24789 (56-167 aa encoded by BC014058)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.47 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: APRKVEPRR SDPGTSGEAY KRSALIPPVE ETVFYPSPYP IRSLIKPLFF TVGFTGCAFG SAAIWQYESL KSRVQSYFDG IKADWLDSIR PQKEGDFRKE INKWWNNLSD GQR (56-167 aa encoded by BC014058)

Target Information

This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Mitochondrial intramembrane cleaving protease PARL; mitochondrial intramembrane-cleaving protease PARL; Presenilin-associated rhomboid-like protein, mitochondrial; rhomboid 7 homolog 1

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Gene Aliases: PARL; PRO2207; PSARL; PSARL1; PSENIP2; RHBDS1

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UniProt ID: (Human) Q9H300

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Entrez Gene ID: (Human) 55486

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Function(s)
endopeptidase activity serine-type endopeptidase activity protein binding
Process(es)
proteolysis protein processing regulation of proteolysis membrane protein proteolysis negative regulation of release of cytochrome c from mitochondria regulation of mitophagy regulation of protein targeting to mitochondrion regulation of reactive oxygen species metabolic process negative regulation of intrinsic apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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