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  • Primary Antibodies ›
  • PAN3 Antibodies

Bethyl Laboratories

PAN3 Polyclonal Antibody

View all (2) PAN3 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite PAN3 Polyclonal Antibody

  • Antibody Testing Data (2)
PAN3 Antibody in Western Blot (WB)
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PAN3 Antibody in Western Blot (WB)
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FIGURE: 1 / 2

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PAN3 Antibody (A304-914A) in WB

Detection of human PAN3 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-PAN3 antibody (Product # A304-914A) (lot A304-914A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PAN3 Antibody in Western Blot (WB)
PAN3 Antibody in Immunoprecipitation (IP)
PAN3 Polyclonal Antibody

Product Details

A304-914A

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000-1:10,000
-

Immunoprecipitation (IP)

2-10 µg/mg lysate
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residue 175 to 225 of human PAB-dependent poly.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

phosphate/tris citrate, pH 7-8

Contains

0.09% sodium azide

Storage conditions

4°C

Shipping conditions

Wet ice

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

PAN3 is functions in cytoplasmic mRNA decay. It is as part of the Pan nuclease complex, recruits polyadenylate-binding protein which in turn stimulates PAN2 nuclease activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: PAB-dependent poly(A)-specific ribonuclease subunit 3; PAB1P-dependent poly(A)-nuclease; PAB1P-dependent poly(A)-specific ribonuclease; PABP-dependent poly(A) nuclease 3; PABP1-dependent poly A-specific ribonuclease subunit PAN3; PAN deadenylation complex subunit 3; PAN2-PAN3 deadenylation complex subunit PAN3; PAN3 poly(A) specific ribonuclease subunit homolog; Poly(A)-nuclease deadenylation complex subunit 3; RP11-179F17.3

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Gene Aliases: PAN3

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UniProt ID: (Human) Q58A45

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Entrez Gene ID: (Human) 255967

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Function(s)
poly(A)-specific ribonuclease activity protein kinase activity protein binding ATP binding poly(A) RNA binding metal ion binding
Process(es)
nuclear-transcribed mRNA poly(A) tail shortening deadenylation-dependent decapping of nuclear-transcribed mRNA mRNA processing protein phosphorylation protein targeting positive regulation of cytoplasmic mRNA processing body assembly RNA phosphodiester bond hydrolysis, exonucleolytic
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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