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Proteintech
PA2G4 Polyclonal Antibody
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Product Details
15348-1-AP
Species Reactivity
Host/Isotype
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Type
Immunogen
Conjugate
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Product Specific Information
This antibody is a rabbit polyclonal antibody raised against full length PA2G4 of human origin.
Immunogen sequence: MSGEDEQQE QTIAEDLVVT KYKMGGDIAN RVLRSLVEAS SSGVSVLSLC EKGDAMIMEE TGKIFKKEKE MKKGIAFPTS ISVNNCVCHF SPLKSDQDYI LKEGDLVKID LGVHVDGFIA NVAHTFVVDV AQGTQVTGRK ADVIKAAHLC AEAALRLVKP GNQNTQVTEA WNKVAHSFNC TPIEGMLSHQ LKQHVIDGEK TIIQNPTDQQ KKDHEKAEFE VHEVYAVDVL VSSGEGKAKD AGQRTTIYKR DPSKQYGLKM KTSRAFFSEV ERRFDAMPFT LRAFEDEKKA RMGVVECAKH ELLQPFNVLY EKEGEFVAQF KFTVLLMPNG PMRITSGPFE PDLYKSEMEV QDAELKALLQ SSASRKTQKK KKKKASKTAE NATSGETLEE NEAGD (1-394 aa encoded by BC001951)
Target Information
This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cell cycle protein p38-2G4 homolog; ErbB-3 binding protein 1; ErbB3-binding protein 1; ErbB3-binding protein Ebp1; hG4 1; hG4-1; IRES-specific cellular trans-acting factor 45 kDa; ITAF45; MGC81621; MGC94070; Mpp1; p38 2G4; proliferation-associated 2G4, 38kD; proliferation-associated 2G4, 38kDa; Proliferation-associated protein 1; Proliferation-associated protein 2G4; Protein p38-2G4; si:dz150i12.2; wu:fb19b11; wu:ft56d05; zgc:86732
Gene Aliases: 38kDa; AA672939; EBP1; HG4-1; p38-2G4; PA2G4; Plfap
UniProt ID: (Human) Q9UQ80, (Rat) Q6AYD3, (Mouse) P50580
Entrez Gene ID: (Human) 5036, (Rat) 288778, (Mouse) 18813
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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