Disclaimer

Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

  • Primary Antibodies ›
  • P2X3 Antibodies

Invitrogen

P2X3 Polyclonal Antibody

View all (17) P2X3 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite P2X3 Polyclonal Antibody

  • Antibody Testing Data (3)
P2X3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Group 53 Created with Sketch.
P2X3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Group 53 Created with Sketch.

FIGURE: 1 / 3

{{ $ctrl.currentElement.advancedVerification.fullName }}
{{ $ctrl.currentElement.advancedVerification.text }}

P2X3 Antibody (PA5-116488) in IHC (P)

Immunohistochemical analysis of P2X3 in a paraffin-embedded rat spinal cord tissue using a P2X3 polyclonal antibody (Product #PA5-116488). The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (1:200) for 30... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
Published figure supplied by benchsci-logo
PMID: {{$ctrl.currentElement.benchSciPubmedId}}
View Product

{{$ctrl.videoDesc}}

{{$ctrl.videoLongDesc}}

P2X3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
P2X3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
P2X3 Antibody in Western Blot (WB)
P2X3 Polyclonal Antibody

Product Details

PA5-116488

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide within mouse P2X3 aa 348-397
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 0.2% BSA, 50% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2901119

Product Specific Information

Positive controls: Mouse testis tissue lysates, rat spinal cord tissue, mouse brain tissue, 293.

Target Information

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: ATP receptor; MGC129956; P2X purinoceptor 3; p2X receptor 3; P2X receptor, subunit 3; P2X3; p2X3 purinoceptor; p2xr3; Purinergic receptor; purinergic receptor P2X, ligand gated ion channel, 3; purinergic receptor P2X, ligand-gated ion channel, 3; purinergic receptor P2X3; purinoceptor P2X3

View more View less

Gene Aliases: 4930513E20Rik; P2RX3; P2X3

View more View less

UniProt ID: (Human) P56373, (Rat) P49654, (Mouse) Q3UR32

View more View less

Entrez Gene ID: (Human) 5024, (Rat) 81739, (Mouse) 228139

View more View less

Function(s)
purinergic nucleotide receptor activity extracellular ATP-gated cation channel activity ATP binding ion channel activity
Process(es)
response to hypoxia ion transport cation transport chemical synaptic transmission neuromuscular synaptic transmission response to temperature stimulus response to heat response to cold response to mechanical stimulus response to carbohydrate response to organic substance urinary bladder smooth muscle contraction neuronal action potential peristalsis response to ATP purinergic nucleotide receptor signaling pathway regulation of synaptic plasticity behavioral response to pain sensory perception of taste protein homooligomerization cation transmembrane transport transport signal transduction blood coagulation positive regulation of calcium ion transport into cytosol positive regulation of calcium-mediated signaling behavioral response to formalin induced pain positive regulation of sensory perception of pain
It has to be done as per old AB suggested Products section.
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support

Your items have has been added!


Host server : magellan-search-55c564d944-rwwh4:80/100.66.128.142:80.
git-commit: 3092084cb0e494f0e07f07633350183de7fa10a8
git-url: https://github.com/thermofisher/magellan-search
git-branch: release/2.36.2-2025.09.39-1.0