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Proteintech
P2RX3 Polyclonal Antibody
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Product Details
17843-1-AP
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: LHEKAYQVR DTAIESSVVT KVKGSGLYAN RVMDVSDYVT PPQGTSVFVI ITKMIVTENQ MQGFCPESEE KYRCVSDSQC GPERLPGGGI LTGRCVNYSS VLRTCEIQGW CPTEVDTVET PIMMEAENFT IFIKNSIRFP LFNFEKGNLL PNLTARDMKT CRFHPDKDPF CPILRVGDVV KFAGQDFAKL ARTGGVLGIK IGWVCDLDKA WDQCIPKYSF TRLDSVSEKS SVSPGYNFRF AKYYKMENGS EYRTLLKAFG IRFDVLVYGN AGKFNIIPTI ISSV (44-326 aa encoded by BC074792)
Target Information
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ATP receptor; MGC129956; P2X purinoceptor 3; p2X receptor 3; P2X receptor, subunit 3; P2X3; p2X3 purinoceptor; p2xr3; Purinergic receptor; purinergic receptor P2X, ligand gated ion channel, 3; purinergic receptor P2X, ligand-gated ion channel, 3; purinergic receptor P2X3; purinoceptor P2X3
Gene Aliases: 4930513E20Rik; P2RX3; P2X3
UniProt ID: (Human) P56373, (Rat) P49654, (Mouse) Q3UR32
Entrez Gene ID: (Human) 5024, (Rat) 81739, (Mouse) 228139
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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