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  • Primary Antibodies ›
  • OLFM1 Antibodies

Invitrogen

OLFM1 Polyclonal Antibody

View all (14) OLFM1 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite OLFM1 Polyclonal Antibody

  • Antibody Testing Data (4)
OLFM1 Antibody in Immunocytochemistry (ICC/IF)
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OLFM1 Antibody in Immunocytochemistry (ICC/IF)
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OLFM1 Antibody (PA5-28842) in ICC/IF

Immunocytochemistry analysis of OLFM1 in methanol-fixed HeLa. Samples were incubated with OLFM1 polyclonal antibody (Product # PA5-28842) using a dilution of 1:500. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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OLFM1 Antibody in Immunocytochemistry (ICC/IF)
OLFM1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
OLFM1 Antibody in Western Blot (WB)
OLFM1 Antibody in Western Blot (WB)
OLFM1 Polyclonal Antibody

Product Details

PA5-28842

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:3,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000
-

Immunocytochemistry (ICC/IF)

1:100-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Noelin. The exact sequence is proprietary.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

0.1M tris glycine, pH 7, with 10% glycerol

Contains

0.01% thimerosal

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2546318

Product Specific Information

Recommended positive controls: HepG2, mouse brain.

Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Chicken (100%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: neuroblastoma protein; Neuronal olfactomedin-related ER localized protein; Noelin; Noelin 1; Noelin 2; olfactomedin related ER localized protein; Olfactomedin-1; Pancortin; pancortin 1; Pancortin 1-4

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Gene Aliases: AMY; AW742568; NOE1; Noel; NOEL1; NOELIN1; OlfA; OLFM1; Pancortin; Pancortin3

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UniProt ID: (Human) Q99784, (Mouse) O88998

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Entrez Gene ID: (Human) 10439, (Mouse) 56177

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Function(s)
protein binding beta-amyloid binding
Process(es)
multicellular organism development protein oligomerization regulation of beta-amyloid formation negative regulation of beta-amyloid formation negative regulation of neuron migration atrioventricular valve formation nervous system development positive regulation of gene expression negative regulation of gene expression positive regulation of epithelial to mesenchymal transition neuronal signal transduction regulation of axon extension cardiac epithelial to mesenchymal transition
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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