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  • Primary Antibodies ›
  • OAS2 Antibodies

OriGene

OAS2 Monoclonal Antibody (OTI2G3), TrueMAB™

View all (32) OAS2 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite OAS2 Monoclonal Antibody (OTI2G3), TrueMAB™

  • Antibody Testing Data (1)
OAS2 Antibody in Western Blot (WB)
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OAS2 Antibody in Western Blot (WB)
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OAS2 Antibody (TA802825) in WB

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OAS2 (RC208273, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-OAS2. Positive lysates LY400905 (100 µg) and LC400905 (20 µg) can be purchased separately from OriGene. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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OAS2 Antibody in Western Blot (WB)
OAS2 Monoclonal Antibody (OTI2G3), TrueMAB™

Product Details

TA802825

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI2G3

Immunogen

Human recombinant protein fragment corresponding to amino acids 60-335 of human OAS2 produced in E.coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates. These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: (2'-5')oligo(A) synthetase 2; (2-5')oligo(A) synthase 2; 2'-5'-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; 2-5A synthase 2; A synthetase 2; MGC78578; p69 OAS / p71 OAS; p69OAS / p71OAS

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Gene Aliases: OAS2

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UniProt ID: (Human) P29728

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Entrez Gene ID: (Human) 4939

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Function(s)
2'-5'-oligoadenylate synthetase activity double-stranded RNA binding protein binding ATP binding metal ion binding
Process(es)
nucleobase-containing compound metabolic process RNA catabolic process protein glycosylation response to virus protein myristoylation defense response to virus interferon-gamma-mediated signaling pathway type I interferon signaling pathway
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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