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Invitrogen
OAS2 Polyclonal Antibody
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Product Details
PA5-65422
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
Immunogen sequence: TLVLFFSDLKQ FQDQKRSQRD ILDKTGDKLK FCLFTKWLKN NFEIQKSLDG FTIQVFTKNQ RISFEVLAAF NALSLNDNPS PWIYRELKRS LDKTNASPGE FAVCFTELQQ K
Highest antigen sequence identity to the following orthologs - mouse 42%, rat 44%.
Target Information
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates. These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: (2'-5')oligo(A) synthetase 2; (2-5')oligo(A) synthase 2; 2'-5'-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; 2-5A synthase 2; A synthetase 2; MGC78578; p69 OAS / p71 OAS; p69OAS / p71OAS
Gene Aliases: OAS2
UniProt ID: (Human) P29728
Entrez Gene ID: (Human) 4939
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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