NeoBiotechnologies

Nucleolin (Marker of Human Cells) Monoclonal Antibody (NCL/7337)

Name: Nucleolin (Marker of Human Cells) Monoclonal Antibody (NCL\/7337)
Brand: NeoBiotechnologies
SKU: 4691-MSM7-P1ABX

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Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (1)

Nucleolin (Marker of Human Cells) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 1

Nucleolin (Marker of Human Cells) Antibody (4691-MSM7-P1ABX) in IHC (P)

Formalin-fixed, paraffin-embedded human colon stained with Nucleolin Mouse Monoclonal Antibody (NCL/7337). HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.

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Immunogen image

Immunogen Image Nucleolin (Marker of Human Cells) Monoclonal Antibody (NCL/7337)

Product Details

4691-MSM7-P1ABX

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG, kappa

Class

Monoclonal

Type

Antibody

Clone

NCL/7337

Immunogen

Recombinant full-length human NCL protein

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS

Contains

no preservative

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Dry ice (international)

Product Specific Information

Positive Control: All human cells. Human testis ovary or Hodgkin s lymphoma.

Cellular Location: Nucleoli.

Target Information

Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: FLJ45706; FLJ59041; nucl antibody; Nucleolin; Protein C23

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Gene Aliases: C23; NCL

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UniProt ID: (Human) P19338

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Entrez Gene ID: (Human) 4691

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Function(s)

nucleotide binding single-stranded DNA binding RNA binding calcium ion binding protein binding protein C-terminus binding selenocysteine insertion sequence binding rRNA primary transcript binding telomeric DNA binding histone binding identical protein binding laminin binding poly(A) RNA binding ErbB-4 class receptor binding

Process(es)

angiogenesis endocytosis spermatogenesis positive regulation of tumor necrosis factor production negative regulation of apoptotic process positive regulation of transcription from RNA polymerase II promoter cellular response to lipopolysaccharide liver regeneration positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter regulation of rRNA processing positive regulation of interleukin-6 secretion

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Nucleolin (Marker of Human Cells) Monoclonal Antibody (NCL/7337)

Nucleolin (Marker of Human Cells) Antibody (4691-MSM7-P1ABX) in IHC (P)

Product Details

4691-MSM7-P1ABX

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

References (0)

Bioinformatics

Performance Guarantee

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