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Invitrogen
Nogo Receptor Recombinant Rabbit Monoclonal Antibody (M5)
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Product Details
MA5-47935
Species Reactivity
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Clone
Immunogen
Conjugate
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Product Specific Information
Specificity: The antibody binds to human and rat NgR1 with a Kd of 2.9 nM for both species (bivalent binding).
Target Information
NOGO (RTN4R) is a receptor for RTN4, OMG, and MAG. Its signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. NOGO also mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult CNS. In addition, NOGO acts with RTN4 and LINGO1 to regulate neuronal precursor cell motility during cortical development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: HGNC:1860; NgR; NgR1; nogo 66 receptor; Nogo receptor; nogo receptor; Nogo-66 receptor; Nogo-66 receptor; Nogo66 receptor; Nogo66 receptor-1; OTTHUMP00000197866; Reticulon-4 receptor; UNQ330/PRO526
Gene Aliases: NGR; NgR1; NOGOR; RTN4R; UNQ330/PRO526
UniProt ID: (Human) Q9BZR6, (Rat) Q99M75, (Mouse) Q99PI8
Entrez Gene ID: (Human) 65078, (Rat) 113912, (Mouse) 65079
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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