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Invitrogen
Nidogen G2 Domain Monoclonal Antibody (JF4)
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Product Details
MA5-17017
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
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Product Specific Information
MA5-17017 recognizes native and denatured mouse and human nidogen, and blocks binding of nidogen to laminin.
MA5-17017 has been successfully used in ELISA and Western blot applications.
The MA5-17017 immunogen is a recombinant fragment corresponding to the G2 region of mouse nidogen produced in Fisher rat plus YB2/0 cells.
Target Information
Basement membrane components play an important role in cell adhesion, locomotion, differentiation and embryonic compartmentalization. Although the precise composition and structure of basal laminae varies from tissue to tissue, as well as within the same tissue at different developmental stages, most mature basal laminae contain type IV collagen, laminins, heparan sulphate proteoglycans and entactin (or nidogen). Entactin is a sulfated glycoprotein that is widely distributed in basement membranes. It is tightly associated with laminin and also binds to collagen IV. Entactin probably has a role in cell-extracellular matrix interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: enactin; Ent 2; Entactin; entactin 1; Entactin 2; NID 2; NID-1; Nid2; Nidogen (enactin); Nidogen 2; Nidogen precursor (Entactin); Nidogen-1
Gene Aliases: A630025O17; Ent; entactin; entactin-1; NID; NID1; nidogen-1
UniProt ID: (Human) P14543, (Mouse) P10493
Entrez Gene ID: (Human) 4811, (Mouse) 18073
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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