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Bioss

Neuropeptide Y Polyclonal Antibody

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite Neuropeptide Y Polyclonal Antibody

  • Antibody Testing Data (1)
Neuropeptide Y Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Neuropeptide Y Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Neuropeptide Y Antibody (BS-0071R) in IHC (P)

Formalin-fixed and paraffin embedded rat brain labeled with Anti-NPY/Neuropeptide Y Polyclonal Antibody, Unconjugated(bs-0071R) 1:400 followed by conjugation to the secondary antibody and DAB staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Neuropeptide Y Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Neuropeptide Y Polyclonal Antibody

Product Details

BS-0071R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:400
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Chicken, Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human NPY, amino acids 29-64.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase, regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Neuropeptide-Y; OTTHUMP00000201947; prepro-neuropeptide Y; Pro-neuropeptide Y; pro-neuropeptide Y-like

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Gene Aliases: 0710005A05Rik; NPY; NPY02; PYY4; RATNPY; RATNPY02

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UniProt ID: (Human) P01303, (Chicken) P28673, (Mouse) P57774, (Rat) P07808

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Entrez Gene ID: (Rat) 100912228, (Human) 4852, (Chicken) 396464, (Mouse) 109648, (Rat) 24604

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Function(s)
neuropeptide hormone activity neuropeptide Y receptor binding G-protein coupled receptor binding G-protein coupled receptor activity receptor binding calcium channel regulator activity hormone activity neuropeptide Y receptor activity
Process(es)
neuropeptide signaling pathway cell-cell signaling feeding behavior regulation of blood pressure regulation of appetite chemical synaptic transmission adult feeding behavior central nervous system neuron development cerebral cortex development neuron projection development positive regulation of appetite negative regulation of blood pressure sensory perception of taste calcium ion transport movement of cell or subcellular component G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger digestion behavior blood circulation cell proliferation
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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