Osenses

Neuroligin 3 Polyclonal Antibody

3 References
View all (20) NLGN3 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

OSN00036W-100UL

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-1:2,000
-

Immunohistochemistry (IHC)

1:300-1:2,000
-

Miscellaneous PubMed (MISC)

-
View 3 publications 3 publications
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide to extracellular domain of human Neuroligin-3 (NLGN3) conjugated to an immunogenic carrier protein was used as the antigen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

The antigen is homologous in rat and mouse.

Specificity of this antibody: NLGN3.

Target Information

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: ASPGX1; AUTSX1; Gliotactin homolog; neuroligin 3 protein; Neuroligin-3

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Gene Aliases: A230085M13Rik; HNL3; KIAA1480; NL3; NLGN3

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UniProt ID: (Human) Q9NZ94, (Mouse) Q8BYM5, (Rat) Q62889

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Entrez Gene ID: (Human) 54413, (Mouse) 245537, (Rat) 171297

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Function(s)
receptor activity protein binding neurexin family protein binding cell adhesion molecule binding carboxylic ester hydrolase activity scaffold protein binding
Process(es)
regulation of respiratory gaseous exchange by neurological system process receptor-mediated endocytosis neuron cell-cell adhesion synapse assembly learning visual learning adult behavior social behavior axon extension oligodendrocyte differentiation modulation of synaptic transmission synapse organization positive regulation of synapse assembly positive regulation of synaptic transmission, glutamatergic rhythmic synaptic transmission excitatory postsynaptic potential inhibitory postsynaptic potential long-term synaptic potentiation positive regulation of dendritic spine development negative regulation of dendritic spine morphogenesis vocalization behavior negative regulation of excitatory postsynaptic potential postsynaptic membrane assembly presynaptic membrane assembly positive regulation of inhibitory postsynaptic potential regulation of long-term synaptic potentiation positive regulation of protein localization to synapse regulation of N-methyl-D-aspartate selective glutamate receptor activity regulation of terminal button organization positive regulation of excitatory postsynaptic potential positive regulation of synaptic vesicle clustering positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity cell adhesion regulation of synaptic transmission, glutamatergic regulation of dendritic spine morphogenesis regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity metabolic process
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