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Neurofilament Recombinant Rabbit Monoclonal Antibody (ZR216), RAbMono™

3 References
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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Neurofilament Recombinant Rabbit Monoclonal Antibody (ZR216), RAbMono™

  • Antibody Testing Data (1)
Neurofilament Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Neurofilament Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 1

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Neurofilament Antibody (Z2706RP) in IHC (P)

Formalin-fixed, paraffin-embedded human cerebellum stained with anti-neurofilament antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of neurons and neuronal processes. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Neurofilament Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Neurofilament Recombinant Rabbit Monoclonal Antibody (ZR216), RAbMono™

Product Details

Z2706RP

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:200
-

Miscellaneous PubMed (MISC)

-
View 3 publications 3 publications
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG1, kappa

Expression System

CHO cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ZR216

Immunogen

Recombinant full-length human NEFL protein
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 µg/mL

Purification

Protein A

Storage buffer

tris with BSA, NP-40

Contains

<0.1% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

This product is diluted and in a ready-to-use formulation.

A recommended positive control tissue for this product is Brain, however positive controls are not limited to this tissue type.

Target Information

Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 200 kDa neurofilament protein; NEF3; neurofilament; Neurofilament heavy polypeptide; Neurofilament triplet H protein; neurofilament, heavy polypeptide 200kDa; NF 200 kD; NF-H; NHC

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Gene Aliases: CMT2CC; KIAA0845; NEFH; NFH

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UniProt ID: (Human) P12036

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Entrez Gene ID: (Human) 4744

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Function(s)
structural molecule activity structural constituent of cytoskeleton microtubule binding toxic substance binding kinesin binding protein kinase binding protein binding, bridging dynein binding protein heterodimerization activity
Process(es)
microtubule cytoskeleton organization ovarian follicle atresia axonogenesis spinal cord development hippocampus development cerebral cortex development cell projection assembly axon regeneration neurofilament bundle assembly cellular response to oxidative stress response to cocaine peripheral nervous system neuron axonogenesis axon development cellular response to estradiol stimulus regulation of organelle transport along microtubule response to sodium arsenite response to acrylamide
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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