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  • NUDT2 Antibodies

Invitrogen

NUDT2 Polyclonal Antibody

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Questions & Answers

Cite NUDT2 Polyclonal Antibody

  • Antibody Testing Data (1)
NUDT2 Antibody in Western Blot (WB)
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NUDT2 Antibody in Western Blot (WB)
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NUDT2 Antibody (PA5-117075) in WB

Western blot analysis of NUDT2 in extracts of various cell lines. Samples were incubated with NUDT2 Polyclonal antibody (Product # PA5-117075) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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NUDT2 Antibody in Western Blot (WB)
NUDT2 Polyclonal Antibody

Product Details

PA5-117075

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human NUDT2 (NP_0011521)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.37 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901705

Product Specific Information

Positive Samples: SKOV3, HL-60, Mouse kidney, Mouse heart, Mouse brain, Mouse liver, Rat kidney, Rat heart

Immunogen sequence: MALRACGLII FRRCLIPKVD NNAIEFLLLQ ASDGIHHWTP PKGHVEPGED DLETALRETQ EEAGIEAGQL TIIEGFKREL NYVARNKPKT VIYWLAEVKD YDVEIRLSHE HQAYRWLGLE EACQLAQFKE MKAALQEGHQ FLCSIEA

Target Information

This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and three transcript variants, all encoding the same protein, have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Ap4A hydrolase; Ap4A hydrolase 1; Ap4Aase; bis(5'-nucleosyl)-tetraphosphatase; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase; diadenosine tetraphosphatase; MGC10404; Nucleoside diphosphate-linked moiety X motif 2; nudix (nucleoside diphosphate linked moiety X)-type motif 2; Nudix motif 2

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Gene Aliases: 2310051L06Rik; AA939917; APAH1; NUDT2

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UniProt ID: (Human) P50583, (Mouse) P56380, (Rat) Q6PEC0

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Entrez Gene ID: (Human) 318, (Mouse) 66401, (Rat) 297998

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Function(s)
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity protein binding GTP binding bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity nucleotide binding bis(5'-nucleosyl)-tetraphosphatase activity hydrolase activity
Process(es)
apoptotic process response to reactive oxygen species nucleobase-containing compound metabolic process metabolic process
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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