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Osenses
NPY Polyclonal Antibody
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Product Details
OSN00016W-150UL
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
The antigen is homologous in many other species including human, rat, zebrafish and xenopus.
Specificity of this antibody: NPY.
Target Information
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase, regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Neuropeptide-Y; OTTHUMP00000201947; prepro-neuropeptide Y; Pro-neuropeptide Y; pro-neuropeptide Y-like
Gene Aliases: 0710005A05Rik; NPY; NPY02; PYY4; RATNPY; RATNPY02
UniProt ID: (Human) P01303, (Mouse) P57774, (Rat) P07808
Entrez Gene ID: (Rat) 100912228, (Human) 4852, (Rabbit) 100301542, (Mouse) 109648, (Rat) 24604
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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