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  • Primary Antibodies ›
  • Nogo-D Antibodies

Osenses

NOGO Polyclonal Antibody

2 References
View all (5) Nogo-D antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite NOGO Polyclonal Antibody

NOGO Polyclonal Antibody

Product Details

OSN00025G-500UG

Applications
Tested Dilution
Publications

Western Blot (WB)

10-50 µg/mL
-

Immunohistochemistry (IHC)

10-50 µg/mL
-

Miscellaneous PubMed (MISC)

-
View 2 publications 2 publications
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from aa region 460-510 of human NOGO conjugated to an immunogenic carrier protein was used as the antigen
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Purification

Ammonium sulfate precipitation

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: Nogo.

Target Information

Required to induce the formation and stabilization of endoplasmic reticulum (ER) tubules. They regulate membrane morphogenesis in the ER by promoting tubular ER production. They influence nuclear envelope expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins. However each isoform have specific functions mainly depending on their tissue expression specificities. Isoform D is expressed at very low levels in neurons.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Foocen; Glut4 vesicle 20 kDa protein; GLUT4 vesicle 20kDa protein; Human NogoA; My043 protein; neurite growth inhibitor 220; Neurite outgrowth inhibitor; Neuroendocrine-specific protein; Neuroendocrine-specific protein C homolog; NI-220/250; Nogo protein; NSP; reticulon 5; Reticulon-4; Reticulon-5; RTN-x

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Gene Aliases: 1110020G17Rik; AA407876; AA409940; AA960376; ASY; C130026I10Rik; KIAA0886; mKIAA0886; mKIAA4153; My043; Nbla00271; Nbla10545; NgA; NI-250; NI220/250; NOGO; NOGO-A; Nogo-B; Nogo-C; NOGOC; NSP; NSP-CL; r; rat N; rat NogoA; RTN-X; RTN4; RTN4-A; RTN4-B1; RTN4-B2; RTN4-C; SP1507; Vp20

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UniProt ID: (Human) Q9NQC3, (Mouse) Q99P72, (Rat) Q9JK11

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Entrez Gene ID: (Human) 57142, (Mouse) 68585, (Rat) 83765

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Function(s)
protein binding poly(A) RNA binding cadherin binding involved in cell-cell adhesion protein complex binding
Process(es)
angiogenesis nervous system development axonogenesis axonal fasciculation negative regulation of neuron projection development cerebral cortex radial glia guided migration negative regulation of cell growth regulation of cell migration negative regulation of axon extension positive regulation of dopamine secretion negative regulation of neuron differentiation positive regulation of glial cell differentiation negative regulation of axonogenesis regulation of sensory perception of pain regulation of nervous system development cardiac epithelial to mesenchymal transition negative regulation of neuron projection regeneration endoplasmic reticulum tubular network organization regulation of branching morphogenesis of a nerve apoptotic process regulation of apoptotic process nuclear pore complex assembly endoplasmic reticulum tubular network assembly cell-cell adhesion aging response to activity olfactory nerve development oligodendrocyte differentiation
It has to be done as per old AB suggested Products section.
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