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NMT1 Monoclonal Antibody (2D9B9)

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite NMT1 Monoclonal Antibody (2D9B9)

  • Antibody Testing Data (4)
NMT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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NMT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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NMT1 Antibody (67984-1-IG150UL) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using (Product # 67984-1-IG150UL) (NMT1 antibody) at dilution of 1:1,000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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NMT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NMT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NMT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NMT1 Antibody in Western Blot (WB)
NMT1 Monoclonal Antibody (2D9B9)

Product Details

67984-1-IG150UL

Applications
Tested Dilution
Publications

Western Blot (WB)

1:5,000-1:50,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:2,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

2D9B9

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Target Information

NMT1 is involved with Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1 MIM 139311).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: alternative, short form NMT-S; Glycylpeptide N-tetradecanoyltransferase 1; HsNMT1; long form, NMT-L; Myristoyl-CoA:protein N-myristoyltransferase 1; NMT 1; Peptide N-myristoyltransferase 1; Protein-lysine myristoyltransferase NMT1; type I N-myristoyltransferase

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Gene Aliases: AW536594; NMT; NMT1

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UniProt ID: (Human) P30419, (Mouse) O70310, (Rat) Q8K1Q0

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Entrez Gene ID: (Human) 4836, (Mouse) 18107, (Rat) 259274

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Function(s)
glycylpeptide N-tetradecanoyltransferase activity myristoyltransferase activity transferase activity transferase activity, transferring acyl groups
Process(es)
in utero embryonic development N-terminal protein myristoylation N-terminal peptidyl-glycine N-myristoylation biological_process regulation of rhodopsin mediated signaling pathway positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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