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  • NMI Antibodies

Abnova

NMI Polyclonal Antibody, MaxPab™

View all (30) NMI antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite NMI Polyclonal Antibody, MaxPab™

  • Antibody Testing Data (6)
NMI Antibody in Immunocytochemistry (ICC/IF)
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NMI Antibody in Immunocytochemistry (ICC/IF)
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NMI Antibody (H00009111-D01P) in ICC/IF

Immunofluorescence of purified MaxPab antibody to NMI on HeLa cell. Antibody concentration is 30 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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NMI Antibody in Immunocytochemistry (ICC/IF)
NMI Antibody in Western Blot (WB)
NMI Antibody in Western Blot (WB)
NMI Antibody in Western Blot (WB)
NMI Antibody in Western Blot (WB)
NMI Antibody in Western Blot (WB)
NMI Polyclonal Antibody, MaxPab™

Product Details

H00009111-D01P

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunocytochemistry (ICC/IF)

30 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

NMI (AAH21987.1, 1 a.a. approximately 307 a.a) full-length human protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MEADKDDTQQ ILKEHSPDEF IKDEQNKGLI DEITKKNIQL RKEIQKLETE LQEATKEFQI KEDIPETKMK FLSVETPEND SQLSNISCSF QVSSKVPYEI QKGQALITFE KEEVAQNVVS MSKHHVQIKD VNLEVTAKPV PLNSGVRFQV YVEVSKMKIN VTEIPDTLRE DQMRDKLELS FSKSRNGGGE VDRVDYDRQS GSAVITFVEI GVADKILKKK EYPLYINQTC HRVTVSPYTE IHLKKYQIFS GTSKRTVLLT GMEGIQMDEE IVEDLINIHF QRAKNGGGEV DVVKCSLGQP HIAYFEE

Target Information

NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: N-mcy (and STAT) interactor; N-myc (and STAT) interactor; N-myc and STAT interactor; N-myc interactor; N-myc-interactor; Nmi

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Gene Aliases: NMI

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UniProt ID: (Human) Q13287, (Mouse) O35309

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Entrez Gene ID: (Human) 9111, (Mouse) 64685

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Function(s)
transcription cofactor activity protein binding
Process(es)
negative regulation of type I interferon production negative regulation of interferon-alpha biosynthetic process negative regulation of interferon-beta biosynthetic process negative regulation of innate immune response positive regulation of protein K48-linked ubiquitination transcription from RNA polymerase II promoter inflammatory response JAK-STAT cascade interferon-gamma-mediated signaling pathway regulation of nucleic acid-templated transcription
It has to be done as per old AB suggested Products section.
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