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  • NME1 Antibodies

Proteintech

NME1 Polyclonal Antibody

11 References
View all (121) NME1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite NME1 Polyclonal Antibody

  • Antibody Testing Data (9)
NME1 Antibody in Immunocytochemistry (ICC/IF)
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NME1 Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 9

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NME1 Antibody (11086-2-AP) in ICC/IF

Immunofluorescent analysis of MCF-7 cells using 11086-2-AP (NME1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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NME1 Antibody in Immunocytochemistry (ICC/IF)
NME1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NME1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NME1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NME1 Antibody in Western Blot (WB)
NME1 Antibody in Western Blot (WB)
NME1 Antibody in Western Blot (WB)
NME1 Antibody in Western Blot (WB)
NME1 Antibody in Immunoprecipitation (IP)
NME1 Polyclonal Antibody

Product Details

11086-2-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
View 6 publications 6 publications

Immunohistochemistry (IHC)

-
View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Immunocytochemistry (ICC/IF)

1:20-1:200
View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

NME1 Fusion Protein Ag1548 (1-152 aa encoded by BC018994)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.35 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MANCERTFI AIKPDGVQRG LVGEIIKRFE QKGFRLVGLK FMQASEDLLK EHYVDLKDRP FFAGLVKYMH SGPVVAMVWE GLNVVKTGRV MLGETNPADS KPGTIRGDFC IQVGRNIIHG SDSVESAEKE IGLWFHPEEL VDYTSCAQNW IYE (1-152 aa encoded by BC018994)

Target Information

NME1 was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in the gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: GAAD; Granzyme A activated DNase (GAAD); Granzyme A-activated DNase; GZMA activated DNase; included; Metastasis inhibition factor nm23; NDK A; NDP kinase A; NM23-H1; NM23H1B; NME1-NME2 spliced read-through transcript; non-metastatic cells 1, protein (NM23A) expressed in; Nucleoside diphosphate kinase A; Tumor metastatic process-associated protein

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Gene Aliases: AWD; GAAD; NB; NBS; NDKA; NDPK-A; NDPKA; NM23; NM23-H1; NME1

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UniProt ID: (Human) P15531

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Entrez Gene ID: (Human) 4830

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Function(s)
magnesium ion binding RNA polymerase II regulatory region sequence-specific DNA binding single-stranded DNA binding deoxyribonuclease activity nucleoside diphosphate kinase activity protein binding ATP binding GTP binding intermediate filament binding protein kinase binding identical protein binding gamma-tubulin binding ribosomal small subunit binding poly(A) RNA binding
Process(es)
negative regulation of myeloid leukocyte differentiation purine nucleotide metabolic process nucleoside diphosphate phosphorylation GTP biosynthetic process pyrimidine nucleotide metabolic process UTP biosynthetic process CTP biosynthetic process DNA metabolic process endocytosis lactation negative regulation of cell proliferation nucleoside triphosphate biosynthetic process negative regulation of gene expression positive regulation of neuron projection development response to amine nucleobase-containing small molecule interconversion hippocampus development response to testosterone cellular response to drug regulation of apoptotic process positive regulation of DNA binding positive regulation of epithelial cell proliferation response to cAMP cellular response to glucose stimulus cellular response to fatty acid
It has to be done as per old AB suggested Products section.
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