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  • NLGN3 Antibodies

Invitrogen

NLGN3 Polyclonal Antibody

Advanced Verification
View all (20) NLGN3 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite NLGN3 Polyclonal Antibody

  • Antibody Testing Data (6)
  • Advanced Verification (1)
NLGN3 Antibody in Immunohistochemistry (IHC)
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NLGN3 Antibody in Immunohistochemistry (IHC)
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NLGN3 Antibody (PA5-51850) in IHC

Immunohistochemical staining of NLGN3 in human cerebral cortex and skeletal muscle tissues using NLGN3 Polyclonal Antibody (Product # PA5-51850). Corresponding NLGN3 RNA-seq data are presented for the same tissues. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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NLGN3 Antibody in Immunohistochemistry (IHC)
NLGN3 Antibody in Immunohistochemistry (IHC)
NLGN3 Antibody in Immunohistochemistry (IHC)
NLGN3 Antibody in Immunohistochemistry (IHC)
NLGN3 Antibody in Immunohistochemistry (IHC)
NLGN3 Antibody in Western Blot (WB)
NLGN3 Antibody
NLGN3 Polyclonal Antibody

Product Details

PA5-51850

Applications
Tested Dilution
Publications

Western Blot (WB)

0.04-0.4 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NLGN3. Recombinant protein control fragment (Product #RP-92260).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2644713

Product Specific Information

Immunogen sequence: APAPTVNTHF GKLRGARVPL PSEILGPVDQ YLGVPYAAPP IGEKRFLPPE PPPSWSGIRN ATHFPPVCPQ NIHTAVPEVM LPVWFTANLD IVATYIQEPN EDCLYLNVYV PTED

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ASPGX1; AUTSX1; Gliotactin homolog; Neuroligin-3

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Gene Aliases: HNL3; KIAA1480; NL3; NLGN3

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UniProt ID: (Human) Q9NZ94

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Entrez Gene ID: (Human) 54413

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Function(s)
receptor activity protein binding neurexin family protein binding cell adhesion molecule binding carboxylic ester hydrolase activity scaffold protein binding
Process(es)
regulation of respiratory gaseous exchange by neurological system process receptor-mediated endocytosis neuron cell-cell adhesion synapse assembly learning visual learning adult behavior social behavior axon extension oligodendrocyte differentiation modulation of synaptic transmission synapse organization positive regulation of synapse assembly positive regulation of synaptic transmission, glutamatergic rhythmic synaptic transmission excitatory postsynaptic potential inhibitory postsynaptic potential long-term synaptic potentiation positive regulation of dendritic spine development negative regulation of dendritic spine morphogenesis vocalization behavior negative regulation of excitatory postsynaptic potential postsynaptic membrane assembly presynaptic membrane assembly positive regulation of inhibitory postsynaptic potential regulation of long-term synaptic potentiation positive regulation of protein localization to synapse regulation of N-methyl-D-aspartate selective glutamate receptor activity regulation of terminal button organization positive regulation of excitatory postsynaptic potential positive regulation of synaptic vesicle clustering positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
It has to be done as per old AB suggested Products section.
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